Treatment of Parkinson's Disease with Stem Cells

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Parkinson's disease (PD) is a progressive neurodegenerative disorder that primarily affects the motor system. The main symptoms of PD include tremors, rigidity, bradykinesia (slow movements), and postural instability. PD is caused by the death of dopaminergic neurons in the substanti

Traditional treatments for PD aim to alleviate symptoms and improve patients' quality of life, including medication (such as levodopa) and surgery (such as deep brain stimulation). However, these treatments do not cure PD or prevent the progression of the disease. In recent years, stem cells have been the subject of active research as a potentially new approach to treating PD, aiming to replace lost dopaminergic neurons and restore brain function https://stemplus.clinic/disease-treatment/parkinson-disease/

Stem cells, particularly neural stem cells (NSCs) and induced pluripotent stem cells (iPSCs), have the ability to differentiate into dopamine-producing neurons. Transplanting stem cells into the striatum, the region of the brain affected by dopamine deficiency in PD, can restore dopamine levels and improve motor functions. Stem cells also secrete neurotrophic factors such as GDNF (glial cell-derived neurotrophic factor).

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