Co-codamol 30/500mg tablets are a commonly prescribed pain relief medication used to manage moderate to severe pain when simpler painkillers are not effective. This combination medicine contains two active ingredients—codeine phosphate (30mg) and paracetamol (500mg)—working together to provide stronger, more effective relief. Because of its opioid content, co-codamol 30/500mg is only available on prescription and should always be used under medical supervision.
This guide explains what co-codamol 30/500mg is, how it works, what it is used for, correct dosage, benefits, side effects, precautions, and important safety information.
What Is Co-codamol 30/500mg?
Co-codamol is a combination analgesic medicine. The “30/500” strength refers to:
30mg Codeine Phosphate – an opioid painkiller
500mg Paracetamol – a non-opioid analgesic and antipyretic (fever reducer)
Together, these ingredients provide more powerful pain relief than paracetamol alone. This strength is considered high-dose co-codamol and is typically prescribed when lower doses or standard painkillers such as paracetamol or ibuprofen are not sufficient.
How Does Co-codamol Work?
Co-codamol works through the combined actions of its two ingredients:
1. Codeine Phosphate
Codeine is an opioid that works in the brain and spinal cord to change how the body perceives pain. It reduces the intensity of pain signals, helping you feel more comfortable.
2. Paracetamol
Paracetamol works by inhibiting the production of certain chemicals in the brain that are responsible for pain and fever. It is gentle on the stomach compared to some other painkillers.
When taken together, these two ingredients provide dual-action pain relief, making co-codamol effective for stronger or persistent pain.
What Is Co-codamol 30/500mg Used For?
Co-codamol 30/500mg is prescribed for moderate to severe pain that does not respond well to weaker painkillers. Common uses include:
Post-operative pain
Dental pain and tooth extractions
Musculoskeletal pain (such as back pain or joint pain)
Injury-related pain (sprains, fractures)
Severe headaches or migraines (in some cases)
Pain following medical or dental procedures
It is usually prescribed for short-term use due to the risk of dependence associated with codeine.
Who Can Take Co-codamol 30/500mg?
Co-codamol 30/500mg in the Uk may be suitable for adults who need stronger pain relief and have been assessed by a healthcare professional. Your doctor will consider your medical history, current medications, and overall health before prescribing it.
It is generally not recommended for:
Children under 18 years
People with breathing problems or severe asthma
Those with liver disease or alcohol dependency
Individuals with a history of opioid dependence
Always follow your doctor’s advice.
Dosage and How to Take Co-codamol 30/500mg
The typical adult dosage is:
1–2 tablets every 4 to 6 hours as needed
Maximum: 8 tablets in 24 hours
Important points:
Swallow tablets with water.
Do not exceed the recommended dose.
Do not take for longer than prescribed.
Avoid taking other medicines containing paracetamol at the same time.
If pain continues or worsens, consult your doctor rather than increasing the dose.
Benefits of Co-codamol 30/500mg
Some key benefits include:
Strong Pain Relief
The combination of codeine and paracetamol provides more effective relief than either ingredient alone.
Fast Acting
Many people experience pain relief within 30–60 minutes after taking a dose.
Suitable for Different Types of Pain
It can be used for various pain conditions, making it a versatile option.
Improved Comfort and Recovery
Effective pain control can help improve mobility, sleep, and overall quality of life during recovery.
Possible Side Effects
Like all medicines, co-codamol 30/500mg can cause side effects. Not everyone will experience them, but it is important to be aware.
Common Side Effects
Drowsiness or sleepiness
Dizziness or light-headedness
Nausea or vomiting
Constipation
Dry mouth
Less Common Side Effects
Headache
Sweating
Confusion (especially in older adults)
Serious Side Effects (Seek medical help immediately)
Difficulty breathing
Severe allergic reactions (swelling, rash, itching)
Extreme drowsiness or unresponsiveness
If you notice any unusual or severe symptoms, contact your healthcare provider promptly.
Risk of Dependence and Addiction
Codeine is an opioid, which means it has the potential to cause dependence or addiction, especially if used for long periods or at higher doses than prescribed.
To reduce this risk:
Use only as directed by your doctor
Do not take for longer than prescribed
Do not share your medication with others
Avoid alcohol while taking co-codamol
If you feel you are becoming reliant on the medication, speak to your doctor for support.
Precautions and Warnings
Before taking co-codamol 30/500mg, inform your doctor if you:
Have liver or kidney problems
Have breathing disorders such as asthma or COPD
Have a history of drug or alcohol misuse
Are pregnant or breastfeeding
Are taking other medications, including antidepressants or sleeping tablets
Co-codamol can interact with other medicines, so always disclose your full medication list.
Co-codamol and Paracetamol Safety
Each tablet contains 500mg of paracetamol. Taking too much paracetamol can cause serious liver damage. Never exceed the daily maximum dose, and avoid combining co-codamol with other paracetamol-containing products such as cold and flu remedies.
If you accidentally take more than the recommended amount, seek medical help immediately—even if you feel fine.
Driving and Operating Machinery
Co-codamol can cause drowsiness, dizziness, and blurred vision. You should:
Avoid driving if you feel sleepy or impaired
Not operate heavy machinery until you know how the medicine affects you
Driving while impaired by medication can be dangerous and illegal.
Use During Pregnancy and Breastfeeding
Co-codamol is not usually recommended during pregnancy, especially in the later stages, as codeine may affect the baby. During breastfeeding, codeine can pass into breast milk and may cause serious side effects in infants.
Always consult your doctor before using co-codamol if you are pregnant or breastfeeding.
How Long Does Co-codamol Stay in Your System?
Codeine is processed in the liver and excreted in urine. It generally stays in the body for about 24–48 hours, but this can vary depending on your metabolism, age, and overall health.
Paracetamol is usually cleared from the body within 24 hours.
Storing Co-codamol Safely
Keep in a cool, dry place
Store out of reach of children
Do not use after the expiry date
Do not share with others, even if they have similar symptoms
Unused tablets should be returned to a pharmacy for safe disposal.
When to See a Doctor
Contact your doctor if:
Pain does not improve after a few days
You experience troublesome side effects
You feel you need higher doses for the same effect
You have concerns about dependence or withdrawal
Your doctor may adjust your treatment or suggest alternative pain management options.
Alternatives to Co-codamol 30/500mg
Depending on your condition, your doctor may consider:
Paracetamol alone
Non-steroidal anti-inflammatory drugs (NSAIDs)
Other opioid or non-opioid painkillers
Physiotherapy, rest, or other supportive treatments
Pain management is individual, and the best option varies from person to person.
Responsible Use and Patient Awareness
Using co-codamol responsibly is essential for your safety and wellbeing. Always:
Follow your prescription
Avoid mixing with alcohol or sedatives
Never crush or chew tablets unless advised
Do not suddenly stop long-term use without medical advice
Being informed helps you get the most benefit while minimising risks.
Final Thoughts
Co-codamol 30/500mg tablets are a powerful and effective option for managing moderate to severe pain when weaker painkillers are not enough. The combination of codeine and paracetamol provides dual-action relief, helping many people recover more comfortably from injury, surgery, or painful conditions.
However, because it contains an opioid, co-codamol must be used carefully and responsibly. Following medical advice, using the correct dose, and being aware of side effects and risks are key to safe treatment.
If you have any doubts or concerns about co-codamol 30/500mg, speak to your doctor or pharmacist. Proper guidance ensures you receive the pain relief you need while protecting your health.
